Old news by now, but, from Wikipedia:

On June 3, 2006 while presenting the award for best movie at the 2006 MTV Movie Awards, Jackson declared that Snakes on a Plane would win the award the following year, jokingly stating:

No movie shall triumph over Snakes on a Plane. Unless I happen to feel like making a movie called More Motherfucking Snakes on More Motherfucking Planes.